Japanese Biologists in discovering microbes that depend on each other and can be used for smell elimination and disintegration.  He also developed and produced micro-biological matters that are small enough to be considered Nano-technology such as bacteriocins and toxins killer, which have the ability to eliminate germs and toxins and producing beneficial enzymes.  Thus, such micro-biological matters were developed to become biotic microbes and being manufactured  by Ana The Nature Co., Ltd.

From his long continuous research, he has contributed his knowledge in litterature titled "The Miracle of Enzymes". The purpose of this book is to educate people about the importance of enzymes. You can make your wise choices for the maintenance of your health.

Questions & Answers about Enzymes:

The Miracle of Enzymes - What are Enzymes?
Enzyme Characteristics
How do enzymes work in our bodies?
Three main categories of enzymes
Important things to remember about enzymes
Health Risk
What is "autointoxication"?
Why are enzymes better for the human body than animal enzymes?
What happens when you are protease deficient? 
What happens when you are lipase deficient?
What cure can enzymes help?
Purchasing enzymes, precription needed?
Enzyme Supplement

 The Miracle of Enzymes - What are Enzymes?
Enzymes are the spark of life – they run your entire body. You couldn’t digest or absorb food, and thus would die without them. Enzymes are specific catalysis with coenzymes (vitamins and minerals) to allow use by your body.
Enzymes also regulate tens of thousands of other biochemical functions that take place in the body every day. Even thinking involves “enzymes” Without enzymes, seeds would not sprout, fruit would not ripen, leaves would not change color, and life would not exist.

Enzymes are protein molecules that carry a vital energy factor needed for every chemical action and reaction that occurs in our bodies. Approximately 2,700 different enzymes are found in human body.
These enzymes can combine with co-enzymes to form nearly one hundred thousand various chemicals that help us to see, hear, feel, move digest food, and think. Every organ, tissue and all the one hundred trillion cells in our body depend upon the reaction of enzymes and their energy factor. Nutrition cannot be explained without describing the vital role played by enzymes. 

  How do enzymes work in our bodies?
When we eat raw foods the enzymes in the food are activated by heat and moisture in the mouth. Once active, these enzymes digest a significant portion of our food and make it small enough to pass through the villi (small projections found in the small intestine) and from t here into the blood. Metabolic enzymes living in the blood take the digested forty-five known nutrients and build them into muscles, nerves, bones, blood, lungs, and various glands.

Every cell in the body depends on a specific group of enzymes. Each enzyme has a particular function which is referred to as enzyme specificity. A protein digestive enzyme will not digest fat; a fat enzyme will not digest starch. Enzymes act upon chemicals and change them into other chemicals, yet remain unchanged themselves. Simply stated; our chemicals are changed from their original identity by the associated enzyme into another chemical with a different identity. Without enzymes, nothing in our bodies would work.

 Three main categories of enzymes :

1. Metabolic enzymes the enzymes within your immune system and the repairers of your human body are part of the metabolic enzymes.
2. Food enzymes the enzymes within live food that help break down that particular food.
3. Digestive enzymes help break down cooked and processed food and breaking down the raw or live food you eat…thus, aiding  the body to make sure your food is properly broken down and your body won’t have to work as hard to get the nourishment out of the food.

Type	Use	Source
Digestive Enzymes	Digest Food	Internal (from our body)
Food Enzymes	Digest Food	External (from the raw food self)
Metabolic Enzymes	Run our Body	Internal (from our body)

 
Digestive enzymes and food enzymes basically serve the same function, that is to digest our food so it can be absorbed through the walls of the small intestine into the blood stream.
From this viewpoint the only real difference between food enzymes and digestive enzymes is where they came from , from inside our body or from the food we eat.

 Important things to remember about enzymes:

• Every living thing produces enzymes.
• Enzymes cat as catalysts to speed the breakdown of foods.
•  An enzyme controls chemical reactions.
• Enzymes are very specific in action. Each enzyme is designed to work on specific types of organic materials.
• Optimum temperature is 45 degrees to 140 degrees. Freezing will not harm enzymes; they will be fully active after thawing.  Temperatures above 140 degrees will destroy enzymes.
• Optimum pH range is 6.0 to 11.0 .The optimum activity varies by enzyme.
• Some enzymes strengthen the immune system and fight viruses and others diseases.
• There are enzymes that regulate the functioning of the heart; others in the retina.
• Enzyme deficiencies are behind genetic diseases.
• Enzymes are energized protein molecules. They are the human body’s life force and are involved in every function of the body. Vitamins, minerals and hormones must have enzymes to work properly.
• Life can not exist without enzymes. Individuals who are enzyme deficient are subject to physical problems disease and degeneration.

 Metabolic Enzyme
Enzymes are responsible in maintaining health and in healing they are our metabolism – the body’s labour force.
Our body makes enzymes called metabolic enzymes. They are responsible for every action that takes place in our body including digestion.
When we eat enzyme-deprived foods, our bodies “steal” metabolic enzymes from other parts of the body and put them to work digesting this food. Yet these enzymes are needed for the proper functioning of the body’s organs and systems. The more we use them to digest food. Rather than letting them do what nature intended them to do, the more we jeopardize our health and vitality.

The resulting metabolic dislocations may be the direct cause of cancer, coronary heart disease, diabetes, and many other chronic incurable diseases.

Metabolic enzymes found in the blood then take the digested 45 known nutrients and build them into muscles, nerves, bones, blood, lungs, and various glands. Every cell in the body depends on certain enzymes. Each enzyme has a specific function in the body which is referred to as enzyme specificity.

Metabolic enzymes catalyze, or spark, the reactions within the cells. The body’s organs, tissues, and cells are run by metabolic enzymes. Without them our bodies would not work.. Among their chores are helping to turn phosphorus into bone, attaching iron to our red blood cells, healing wounds, thinking, and making a heart beat.
These Enzymes are instrumental in the growth of new cells and the maintenance of all tissue.They assist in fighting aging, weight loss, lowering cholesterol, cleaning the colon, breaking down fats, strengthening the immune system, improves mental capacity, detoxifying the body, building muscles from protein, eliminating carbon dioxide from the lungs etc.
The foregoing avalanche of relevant information supports the recently discovered law of the adaptive secretion of digestive enzymes which proclaims that the body values enzymes highly and produces no more of them than it is forced to. It more digestive food enzymes are eaten, the body will automatically make fewer digestive enzymes and can then produce more metabolic enzymes, should they be needed. The body will therefore be in a better position to prevent or deal with the problem of killer diseases.
There are between 200-3000 enzymes in a cell. Different cells can have different enzymes. This is why cells look different and perform different functions.

 Food Enzyme
Nature has placed enzymes in food to digest everything you eat starches, fat, protein, fiber, sugars and daily foods instead of forcing the enzymes secreted in our bodies to do all of the work.
Eating raw fruits and vegetables because they are “live foods”; that is, foods in which the enzymes are active. The more enzymes you get, the healthier you are. And the more raw foods you eat, the more enzymes you get. When we eat cooked or processed foods we’re eating dead or denatured foods. Dead foods have no living enzymes and most nutrients are diminished significantly.
There are seven categories of food enzymes:
1. Lipase -->break down fat
2. Protease -->break down protein
3. Cellulase -->break down fiber
4. Amylase --> break down starch
5. Lactase --> break down dairy foods
6. Sucrase --> break down sugars
7. Maltase --> break down grains
In humans, the upper portion of the stomach is in fact a food-enzyme stomach. This part secretes no enzymes. In fact, the digestion of the protein, carbohydrate, and fat in raw food begins in the mouth the very moment the plant cell walls are ruptured, releasing the food enzymes during the act of mastification (chewing). Proper digestion occurs when a good portion of the food is broken down within the first 45 to 60 minutes after swallowing
Every time we put dead food in our body, the body must deal with digesting 100% of the food instead of 50%. This means you are doubling the body’s work every time you eat dead food.

 Digestive Enzyme
As we get older, there is a definite decline in the level of digestive enzymes produced in stomach, pancreas and small intestine usually after age 30-35. Though the reason for this is not clear, it is an established medical fact.

When the nutrients within the food are complete digested  the stool will be light and fluffy and will float. With a good enzyme product most people will see their stool float within a couple of weeks to a month. It may take a little longer for some. Floating stool is a good sign!
Your pancreas manufacture these enzymes and you also obtain some of them from your food. Unfortunately, since so much of our diet is processed foods and contains very little enzyme activity, the pancreas has to work extra hard to try and keep up with the demand for enzymes that are not present in your food.
The two most important digestive enzymes secreted by the human body are amylase and protease. They help with the digestion of carbohydrates and proteins. Saliva supplies a high concentration of amylase, while stomach juice contains protease, The pancreas secretes both in high concentrations along with the enzyme lipase. Lipase deals with fats. The pancreas also secretes maltase, which reduces maltose to dextrose.
Digestive Enzymes are secreted along the gastrointestinal tract and break down foods, enabling the nutrients to be absorbed into the bloodstream for use in various bodily functions. 

IMPORTANT: Digestive enzymes and food enzymes basically serve the same function, that is to digest our food so it can be absorbed through the walls of the small intestine into the blood stream. From this viewpoint the only real difference between food enzymes and digestive enzymes is where they come from - from inside our body or from the food we eat.

Although enzymes are found in small quantities, they are extremely powerful – 30 grams of pure crystalline pepsin would digest nearly 2 metric tons of egg white in a matter of hours.

The second category of enzymes is comprised of digestive enzymes, which can be separated into intrinsic and extrinsic digestive enzymes. Intrinsic digestive enzymes are those that the body manufactures and secretes to break down food. The salivary glands in the stomach and specific cells in the pancreas secrete the enzymes that work to digest the proteins, fats and sugars present in any food that is eaten. Examples of digestive enzymes are protease, which digests protein; amylase which digests starch; and lipase, which digests fat. Since protein conversion is necessary for glucose in the body, a problem with protein digestion can lead to hypoglycemia, irritability as well as mood swings.

 Health Risk
Unfortunately, few food enzymes available in fresh, raw foods are still alive when we finally eat our food. We kill these enzymes with cooking, chemical preservatives, irradiation, and other processing and preservation methods.

The result? Many of the foods (and even nutrition supplements) that we eat pass through and out of our bodies not fully digested. Our bodies do not get many of the nutrients they offer. Thus, we literally “starve” ourselves for wholesome nutrition, even while we’re engorging our bodies.

Our foods are processed, canned, pasteurized, baked, roasted, stewed, boiled, broiled, fried, cooked, dried, burned, chemicalized, embalmed, preserved and microwaved. All of these things kill all enzyme activity in the foods, making these foods indigestible, ready to rot and turn poisonous.

The source of most health problems can be traced directly back to improperly digested foods.

 What is "autointoxication"?
When food remains undigested in the colon for over 6 hours, it begins to putrefy. In other words, germs invade the food and it begins to rot within us. This purification process results in the production of toxic and poisonous waste in the colon. The blood capillaries to the colon pick up the toxins, poisons and debris ass it sweeps through the bowel wall and delivers it to the bloodstream, which delivers it to every organ in the body. This simply means that constipation is actually a process of self-poisoning the entire body. In medical terms, this is called “autointoxication”.

 Why are enzymes better for the human body than animal enzymes?
Enzymes from animals like trypsin, pepsin and pancreatin work in a very narrow pH range and work to a limited degree in the stomach and small intestines, but don’t do anything for digestion in the upper part of the stomach…when the pH is too high, they are inactive. Papaya produces an enzymes are much more effective in the pH and temperature range of the body and they help digest the cooked and raw foods in the upper part of the stomach. These  helps decrease and conserve the digestive enzyme secretion from body needed for digestion.

 What happens when you are protease deficient? 
Protease digests protein.  You will have protein deficiency symptoms, depending on how deficient you are in protease. Protease deficiency creates alkaline excess in the blood.

Because protein is converted to glucose upon demand, inadequate protein digestion leads to hypoglycemia, resulting in moodiness, mood swings and irritability.
Protease also has an ability to digest unwanted debris in the blood including certain bacteria and viruses. Therefore, protease deficient people are immune compromised, making them susceptible to bacterial, viral and yeast infections and a general decrease in immunity.

Another of the most common results of protein maldigestion is chronic ear infections and fluid in the ears, especially in children. This is a protease calcium deficiency. To drain fluids from the middle ear, you must increase protease in the blood.
All pathogens (virus, fungus and bacteria) are made up of protein, or use a protein coating to protect themselves (as virus does).
The enzyme protease breaks down proteins, and since the invaders of our blood system are protein, it makes sense that ingesting protease could break down the protein invaders.
Protease, the enzyme that digests proteins, has a very different and powerful function when on an empty stomach. It is a tremendous all natural blood enhancer, able to break down protein invaders in the blood supply, so that your natural immune system can destroy them.

 What happens when you are lipase deficient?
LIPASE DEFICIENCY CONDITIONS: Since lipase digests fat and fat-soluble vitamins, lipase deficient people can be expected to have a tendency towards high cholesterol, high triglycerides, difficulty losing weight and diabetes or a tendency towards glucosuria (sugar in the urine without symptoms of diabetes). The down-the-road outcome of these tendencies is heart disease.

 What cures can enzymes help?
Many people are familiar with enzymes as digestive aids, but enzymes can also be used to treat a wide variety of conditions though systemic enzyme therapy. These conditions include: premature aging; arthritis and other inflammatory conditions ; cancer; cardiovascular diseases; circulatory problems; gynecological problems; herpes: injuries; multiple sclerosis; skin problems; lupus erythematosus and other autoimmune diseases; viruses and weight problems.

 Purchasing enzymes, prescription needed?
In the United States, the Food and Drug Administration (FDA) has classified enzymes as a food. Therefore, they can be purchased without a prescription. However, insurance coverage is usually dependent upon the therapy resulting from a doctor’s orders.

 Enzyme Supplement
Using supplemental enzymes to promote digestion reduces our need to produce digestive enzymes allowing our body to produce the metabolic enzymes needed to operate efficiently.

• Enzyme supplements are not destroyed by stomach acid. (It was thought and taught that enzyme supplements could not be useful because they were destroyed in the hostile environment of the stomach).
• Anyone who eats cooked or processed food requires supplementation to assist digestion.
• So far as science has been able to discover, the only function any vitamin has is the role it plays in supporting enzymes.
•  Vitamins and minerals are co-enzymes meaning they require an enzyme to work.
• Continue to supplement with vitamins, ionic mineral and any additional nutrients you believe are very good building materials.
• When you add digestive enzymes to your supplementation, your vitamins will work better, the ionic minerals will work better and you’ll get a lot more out of the nutrients you’re taking.
• Enzymes are just as important as vitamins, minerals or any other nutrient, because enzymes are the workforce and life-force of the human body.

The best way to achieve optimal health is by having enzyme levels in the body and conserving the body’s enzyme levels. When the body has an abundance of enzymes, it can protect itself and repair damage from virtually all degenerative disease disorders!
The importance of enzymes cannot be overemphasized. If the enzymes can cause disease, then adding enzymes to the diet, through supplementation and proper food intake will prevent premature aging and break down of the body.

At the Michael Reese Hospital in Chicago experiments were performed on two groups of people. The people in the first group were 21-31 year old. Those in the second group were 69-100 year old. The researchers found that younger people had 30 times more amylase, (the enzyme that breaks down carbohydrates), in their saliva then the older.

As we age, enzyme production slows. Combine this with the fact that our diets now include many processed foods that contain little or no enzymes. Raw foods are plentiful and enzymes laden, but enzymes are sensitive to heat. Cook a meal and you lose the valuable enzymes that were there. If you consume a diet that is largely processed or cooked then you are missing a vital piece of the nutrition puzzle.

This happens because the cooked food won’t digest properly and travels, undigested, into the small intestine. (Once we cook food at high temperatures of 118 degree F. or more, enzymes are destroyed and no longer work.) It’s the beginning of the toxemia cycle (undigested food putrefying in the tract that continues to poison the blood), which is the root of all disease.

 Coenzyme
Micronutrients are the nutrients needed by the body in small amounts as compared with macronutrients (proteins, carbohydrate and fats). They include vitamins, minerals, amino acids and essential fatty acids (EFAs). Vitamins and minerals serve as structural components of tissues. Both function as coenzymes that facilitate thousands of biochemical reactions in the body.
Vitamins serve as co-enzymes, producing many reactions which promote digestion and other functions in the body. Vitamin A aids the respiratory system. The skin, and the glands. It is found in organic foods like greens and sweet potatoes. The B complex vitamin (B2, B6, and B12) have as many as eleven different functions including correcting eye and nervous disorders and swollen parts of the body. These vitamins, in conjunction with the enzymes, also give energy to the brain.

 Energy factor
The  energy factor is the energy that triggers or starts the chemical reactions between enzymes and other substances in the body.  This energy factor is separate and distinct from the chemical makeup of the enzyme itself.  A good example of this energy factor can be observed by placing a raw bean into a pot of boiling water. The cooked bean will fail to sprout. Its life force (energy factor) has been removed.

Science  tells  us  that  only  living  organisms  can make enzymes with this energy factor. Chemicals that serve as catalysts work by chemical action only, while enzymes function by both biological and chemical action. Catalysts do not contain the energy  factor which is  measured  as a kind of radiant energy emitted by  enzymes. The  energy  factor  of  enzymes  has   never been synthesized. Simply   stated: The energy factor is the electricity that makes the light bulb (the enzyme) work.

 Nutrition the  body’s ability  to  consume the forty - five known nutrients in their proper amounts, digest these nutrients, absorb them, carry them into the cells, metabolize these nutrients, and eliminate the waste without getting fat. The following is a list of the forty-five known nutrients.
•   Carbohydrate
•   Lipids (fats)
•   Protein
•   Water
•    9 Amino Acids
•   13 Vitamins
•   19 Minerals
Eating these foods, (which includes ingesting their enzymes) in their proper amounts, will normally ensure good nutrition. Enzymes are responsible for digestion, absorption, transporting, metabolizing, and eliminating the waste from  these nutrients. Again, every organ, every tissue, and all of the one hundred trillion cells in our body depend upon the reactions of enzymes and their energy factor.

 Insulin The pancreatic hormone that regulates the transport of glucose-blood sugar into the cells.

 Refined  Carbohydrates : They are foods such as white flour, cornstarch  or white rice. The enzymes have been destroyed by the refining process. These refined carbohydrates are processed by the body  the same as any  other food, and yet they contain no vitamins or minerals. If we eat them, we must draw upon our own  store of  nutrients normally used in metabolism, thus depleting them. Some people say they do  not eat refined sugar, but if you eat flour, cornstarch, white rice, potato starch, bread, crackers, or pasta- you eat sugar! Milk, yogurt, and other daily products contain sugar in the from of  lactose. In fruit and juices, the sugar is  glucose and fructose. Learn to recognize these different forms  of  sugar when you are reading labels at the supermarket.

 Enzyme Characteristics
• Lower the energy of activation.
• Form reversible complex with substrate.
• Not consumed in the reaction therefore they are effect in small amounts.
• Very specific – (Induced fit hypothesis) react with only a single substrate.
• Many need cofactors, such as certain vitamins, to be activated.
• 2000+ enzymes per cell, different cells have different enzymes.
• Enzymes are produced by genes.
• Genetic disorders are the result of faulty enzymes.
• Operate best in optimum conditions of pH, temperature, etc.
• Are controlled by feedback mechanisms.
• Allosteric Modulation.
• Can be “fooled” by inhibitors – Useful in chemotherapy.